Principal Investigator

Lab Members
Home > Research
Principal Investigator

EDUCATION
-
1987 - 1991 B.S. College of Pharmacy, Seoul National University
-
1991 - 1993 M.S. Major in Pharmacology, Department of Pharmacy, Graduate School, Seoul National University
-
1993 - 1997 Ph.D. Major in Pharmacology, Department of Pharmacy, Graduate School, Seoul National University
CAREER
-
2011 - 현재 교수, 가톨릭대학교 약학대학
-
2004 - 2011 조교수/부교수, 영남대학교 약학대학
-
1999 - 2003 Postdoctoral Fellow/Research Associate, Johns Hopkins University
-
2020 - 현재 BK21FOUR 스마트파마 미래인재 양성사업팀 팀장
-
2025 대한약학회 교육위원장, 한국독성학회 편집위원장(Toxicological Research, Editor-in-Chief), Archives Pharmacal Research (Associate Editor), 한국응용약물학회 기금관리위원장, 식품의약품안전평가원 위해성평가 전문위원
SELECTED PUBLICATIONS (from 2019)
Listed in Stanford/Elsevier’s World’s Top 2% Scientists (Career & 2024)
H-index 50
Scopus : https://www.scopus.com/authid/detail.uri?authorId=7006129122
Orcid : https://orcid.org/0000-0001-6254-2516
-
Kim SK, Bae GS, Bae T, Ku SK, Choi BH, Kwak MK (2024) Renal microRNA-144-3p is associated with transforming growth factor-β1-induced oxidative stress and fibrosis by suppressing the NRF2 pathway in hypertensive diabetic kidney disease. Free Radic Biol Med 225:546-559 (IF=7.1, JIF 랭킹 상위 7.8%)
-
Lee JH, Hallis SP, Kwak MK (2024) Continuous TNF-α exposure in mammary epithelial cells promotes cancer phenotype acquisition via EGFR/TNFR2 activation. Arch Pharm Res. 47(5):465-480 (F=6.9, JIF 랭킹 상위 3.5%).
-
Ham S, Choi BH, Kwak MK (2024) NRF2 signaling and amino acid metabolism in cancer. Free Radic Res. 58(10): 648-661 (IF=3.6)
-
Bae T, Hallis SP, Kwak MK (2024) Hypoxia, Oxidative Stress, and the Interplay of HIFs and NRF2 Signaling in Cancer. Exp Mol Med. 56(3):501-514 (IF=9.5, JIF 랭킹 상위 6.6%)
-
Hallis SP, Kim JM, Kwak MK (2023) Emerging Role of NRF2 Signaling in Cancer Stem Cell phenotype. Mol Cells 46(3):153 (IF=3.7)
-
Hallis SP, Kim SK, Lee JH, Kwak MK (2023) Association of NRF2 with HIF-2α-induced cancer stem cell phenotypes in chronic hypoxic condition. Redox Biol 60:102632 (F=10.7, JIF 랭킹 상위 5.3%).
-
Choi BH, Ryoo I, Shim KH, Ahn HJ, Lee YJ, Kwak MK (2022) High Levels of Hyaluronic Acid Synthase-2 Mediate NRF2-Driven Chemoresistance in Breast Cancer Cells. Biomol Ther 30(4):368.
-
Park J, Kim SK, Hallis SP, Choi BH, Kwak MK (2022) Role of CD133/NRF2 Axis in the Development of Colon Cancer Stem Cell-Like Properties. Front Oncol 2021.808300
-
Choi BH, Kim J, Kwak MK (2021) The multifaceted role of NRF2 in cancer progression and cancer stem cells maintenance. Arch Pharm Res 44(3):263-280 (F=6.9, JIF 랭킹 상위 3.5%).
-
Ryu D, Lee JH, Kwak MK (2020) level is negatively correlated with TGF-beta 1-induced lung cancer motility and migration via NOX4-ROS signaling Arch Pharm Res 43(12): 1297 (F=6.9, JIF 랭킹 상위 3.5%).
-
Kim SK, Kim G, Choi BH, Ryu D, Ku SK, Kwak MK (2021) Negative correlation of urinary miR-199a-3p level with ameliorating effects of sarpogrelate and cilostazol in hypertensive diabetic nephropathy. Biochem Pharmacol. 184:114391 (IF=5.3, JIF 랭킹 상위 9.7%)
-
Lee S, Hallis SP, Jung KA, Ryu D, Kwak MK (2019) Impairment of HIF-1α-mediated metabolic adaption by NRF2-silencing in breast cancer cells. Redox Biol. 24: 101210 (F=10.7, JIF 랭킹 상위 5.3%).
-
Song MK, Lee JH, Ryoo IG, Lee SH, Ku SK, Kwak MK (2019) Bardoxolone ameliorates TGF-β1-associated renal fibrosis through Nrf2/Smad7 elevation. Free Radic Biol. Med 138: 33 (IF=7.1, JIF 랭킹 상위 7.8%)








